Kuyamba kwa Type II Collagen

Type II collagen ndi chiyani?

Type II collagen ndi mapuloteni a fibrillar opangidwa ndi maunyolo aatali atatu a amino acid omwe amapanga ukonde wodzaza kwambiri wa ulusi ndi ulusi. Ndilo gawo lalikulu la cartilage m'thupi. Amakhala ndi kulemera kowuma ndi kolajeni.

Mtundu wachiwiri wa collagen ndi umene umapangitsa kuti cartilage ikhale yolimba komanso yolimba, motero imathandiza kuti mafupa azitha. Zimathandizira pakumanga ndi chithandizo cha fibronectin ndi ma collagen ena.

Kodi pali kusiyana kotani pakati pa Type II ndi Type I collagen?

Pamwamba zimawoneka zofanana, iliyonse ili ndi helix katatu ie yopangidwa ndi maunyolo atatu aatali a amino acid. Komabe, pamlingo wa maselo pali kusiyana kwakukulu.

Type I collagen: Awiri mwa maunyolo atatu ali ofanana.

Type II collagen: Maunyolo onse atatu ndi ofanana.

Type I Collagen imapezeka makamaka m'mafupa ndi khungu. Pamene mtundu II collagen amapezeka mu chichereŵechereŵe.

Kodi mtundu wachiwiri wa collagen umagwira ntchito bwanji m'thupi?

Monga taonera, mtundu wachiwiri wa collagen ndi gawo lalikulu la minofu ya cartilage. Choncho kuti munthu amvetse bwino ntchito yake, ayenera kuyang’ana ntchito ya chichereŵechereŵe m’thupi.

Cartilage ndi minofu yolimba koma yokhazikika. Pali mitundu yosiyanasiyana ya cartilage m'thupi, iliyonse ili ndi ntchito yake. Chichereŵechereŵe chomwe chimapezeka m'malo olumikizirana mafupa chimakhala ndi ntchito zingapo, monga

- kugwirizana mafupa

- kulola minofu kunyamula kupsinjika kwamakina

- mayamwidwe mantha

- kulola mafupa olumikizidwa kuyenda popanda kukangana

Cartilage imapangidwa ndi ma chondrocytes omwe ndi maselo apadera omwe amapanga zomwe zimadziwika kuti 'extracellular matrix' zomwe zimakhala ndi proteoglycan, elastin fibers ndi type II collagen fibers.

Mtundu wa II collagen fibers ndiye chinthu chachikulu cha collagenous chomwe chimapezeka mu cartilage. Amagwira ntchito yofunika kwambiri. Amapanga ukonde wa ma fibrils omwe amathandiza kulumikiza ulusi wa proteoglycan ndi elastin kukhala minofu yolimba, koma yosinthika.